Life course of obesity drugs

Nature, Published online: 19 March 2026; doi:10.1038/d41586-026-00852-xMuscle mass increased or remained stable relative to body weight in middle-aged mice and humans on GLP-1 drugs.

Life course of obesity drugs
Life course of obesity drugs Photo: Nature News

Muscle (pink; artificially coloured) does not decline steeply in middle-aged individuals taking obesity drugs.

Credit: Steve Gschmeissner/SPL
Muscles keep their strength after substantial weight loss following treatment with the new generation of obesity drugs 1 .

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doi: https://doi.org/10.1038/d41586-026-00852-x
Langer, H.

T.

et al.

Cell Rep.

Med.

7 , 102665 (2026).

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